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ROS1 (p.G2032R)

Variant Data

Location

  • HGVS: ENST00000368508:c.6094G>A
  • Reference Version: GRCh37
  • Chromosome: 6
  • Start: 117638347
  • Stop: 117638347
  • Strand: -1
  • Transcript: ENST00000368508 (ensembl - 74_37)
  • Gene: ROS1 ( View drug interactions on DGIdb )

Information

Disease Data

Disease Source Batch Tags External Links
lung adenocarcinoma Awad et al., 2013, N. Engl. J. Med. Drug Gene Knowledge Database (View variants) likely pathogenic Civic logo CIViC
non-small cell lung carcinoma Song et al., 2015, Clin. Cancer Res. CIViC Knowledgebase (View variants) Civic logo CIViC
non-small cell lung carcinoma Davare et al., 2015, Proc. Natl. Acad. Sci. U.S.A. CIViC Knowledgebase (View variants) Civic logo CIViC
non-small cell lung carcinoma Katayama et al., 2015, Clin. Cancer Res. CIViC Knowledgebase (View variants) Civic logo CIViC
non-small cell lung carcinoma Zou et al., 2015, Proc. Natl. Acad. Sci. U.S.A. CIViC Knowledgebase (View variants) Civic logo CIViC

Drug Interaction Data

Therapeutic Context Pathway Effect Association Status Evidence Source
crizotinib activation gain-of-function case report emerging 23724914
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